Control of the cyanobacterial day-night metabolism of Synechocystis sp. PCC 6803 by its biological clock system
When cyanobacteria are grown in a 24 h diurnal cycle, they perform photosynthesis and CO2 fixation during the day and switch to a heterotrophic metabolism in the dark by degrading the glycogen reserves that were synthesized during the light period. Based on our previous studies of biological clock systems, we conclude that the model cyanobacterium Synechocystis 6803 involves homologs of the known canonical central and output clock components to control the switch between autotrophic (in the light) and chemoheterotrophic (in the dark) metabolic modes. Within the scope of the SCyCode programme, we want to elucidate the mechanism of integration of light and nutrient conditions, time information and metabolic signals in the control of cyanobacterial diurnal metabolism.
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Prof. Annegret Wilde
University of Freiburg
Institute of Biology III
Molecular Genetics of Prokaryotes
Schänzlestr. 1, 79104 Freiburg, Germany
Nina Scheurer M.Sc.
Kim Nadine Sebastian
Dr. Christin Köbler